The UCLA-DOE Institute for Genomics and Proteomics serves a long-standing goal on the UCLA campus to bring frontier research efforts to bear on key scientific mission areas for the U.S. Department of Energy.  Over its history, the Institute has led numerous scientific developments, with discoveries and technological innovations impacting the DOE, the U.S. national laboratories, and the scientific community broadly.

The Institute comprises some dozen leading faculty members and their laboratories, assembled for their world-leading expertise in diverse but connected areas: plants and microbes; photosynthesis and regulation; enzymes and biochemical pathways; genomics and proteomics; atomic structure and molecular design.

The Institute’s mid-range operational size makes it possible for scientific investigators to form small collaborative teams with complementary expertise, while remaining agile enough to move in new directions dictated by novel discoveries and evolving scientific needs.

Technology development and dissemination form central pillars of the Institute.  Scientific challenges drive innovative technologies in the Institute, which has been at the leading edge of methods developments in computational and experimental genomics, macromolecular structure and imaging, metabolic engineering, and macromolecular design.  The Institute fosters and spreads technology innovation through support of a set of Core facilities: Protein Expression; Crystallography and Macromolecular Structure Determination; Biochemical Instrumentation; and Macromolecular NMR.

The Institute also emphasizes the critical role of scientific training and outreach, within the Department of Energy as a focal point of US science, and for society generally.  To meet that need the Institute engages actively in teaching across the spectrum of stakeholders, from professional scientists in training all the way to elementary student groups.  The broad scope of scientific training activities in the Institute significantly deepens the long-term impact of the Institute.

The current research goals of the UCLA-DOE Institute are being carried out through teams focusing on major scientific challenges in four areas: Algal Functional Genomics; Microbial Metabolism and Communities; Synthetic Biology; and Atomic Imaging and Emerging Technologies.

”The UCLA-DOE Institute provides a unique system on campus for organizing frontier research to address key scientific, national, and societal needs.” 

– Todd Yeates, Director