IGP Core

Biocomputing Technology

CORE MANAGER: DUILIO CASCIO

Phone: (310) 825-1551

Email:  cascio@mbi.ucla.edu

Boyer Hall 220, 611 Young Drive East, Los Angeles, CA 90095

Staff:

Alex Lisker   lisker@mbi.ucla.edu    (310) 206-3916

Tom Holton  holton@mbi.ucla.edu

Services Provided

  1. Evaluation, purchase, set up, and maintenance of the computer hardware and network for the 170 users in the research groups of the PIs and Associate Members of the Division of Structural Biology and Genetics.
  2. Development and acquisition of software and installation and maintenance of software for the Division of Structural Biology and Genetics, including programs for the determination, display, and interpretation of molecular structures.
  3. In-person instruction in the use of hardware, software and graphics.
  4. Development and maintenance of the World Wide Web sites of the Division of Structural Biology and Genetics and partnering units, including the home-grown UCLA-DOE web servers, FAES, Twin Detection, Diffraction Anisotropy Server, Surface Entropy Reduction Server, Structure Verification servers such as ERRAT, Verify3D, and other programs for sequence and structure analysis (SAVES).
  5. Maintenance of publicly accessible databases developed in the Division such as  the MCPdb (Bacterial Microcompartment Database), DIP (Database of Interacting Proteins), Amyloid Atlas  LARKSdb, ZipperDB, and of databases and programs for internal use.

Facilities and Equipment

A network of servers and graphic workstations has been established, made up of an HPC cluster of 100 Multicore Linux compute servers, 54 GPU servers using the SLURM workload manager and queuing system and 72 Linux workstations, which are connected together by a high speed network of fiber optics. All the web, mail, SQL  servers and  Petabyte storage systems, are housed in air-conditioned computer rooms.

The BioComputing Technology Core is supported by a professional staff of two, who maintain both hardware and software and are available on demand to help when needed. With oversight from the core manager, the staff works with an enormous range of user skills, from professional programmers to complete novices. When new programs or systems are introduced, the core often provides classes for groups and in-person training of new users.