X-ray Crystallography Condition Screening Core Technology Center

I joined the institute in June of 2012. This is a great community to be a part of and I am proud to be here. Each year we continue finding new ways to advance our motivated researchers, and push forward with new technologies and methods. I manage operations in the crystallization and x-ray crystallography cores while supporting the computer graphics core as needed. I am enrolled full time in Washington State University’s Carson School of Business and expect to finish my MBA in 2019.


Mustafa Ugur Daloglu, Aniruddha Ray, Michael J. Collazo, Calvin Brown, Derek Tseng, Blanca Chocarro-Ruiz, Laura M. Lechuga, Duilio Cascio & Aydogan Ozcan. (2019). Low-cost and portable UV holographic microscope for high-contrast protein crystal imaging. APL Photonics. 4. doi:

Chen, Wenyang & Mandali, Sridhar & Hancock, Stephen & Kumar, Pramod & Collazo, Michael & Cascio, Duilio & C Johnson, Reid. (2018). Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition. eLife. 7. 10.7554/elife.39611.

Irina V. Novikova, Noopur Sharma, Trevor Moser, Ryan Sontag, Yan Liu, Michael J. Collazo, Duilio Cascio, Tolou Shokuhfar, Hanjo Hellmann, Michael Knoblauch, James E. Evans
“Protein Structural Biology Using Cell-Free Platform from Wheat Germ.” BioRx. July 23, 2018, doi:

Michael R. Sawaya, Jose Rodriguez, Duilio Cascio, Michael J. Collazo, Dan Shi, Francis E. Reyes, Johan Hattne, Tamir Gonen, and David S. Eisenberg
“Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.”
PNAS 2016 113 (40) 11232-11236; published ahead of print September 19, 2016, doi:10.1073/pnas.1606287113

Nicole M Wheatley, Kevin D Eden, Joanna Ngo, Justin S Rosinski, Michael R Sawaya, Duilio Cascio,Michael Collazo, Hamidreza Hoveida, Wayne L Hubbell, and Todd O Yeates
“A PII-Like Protein Regulated by Bicarbonate: Structural and Biochemical Studies of the Carboxysome-Associated CPII Protein.”
J Mol Biol Jul 25. Epub Jul 25. (2016)

Jeffery M Vinokur, Tyler P Korman, Michael R Sawaya, Michael J Collazo, Duilio Cascio, and James U Bowie
“Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases.”
Protein Sci. (2015) 24: 212-220

Michael J Collazo, Soheila Vaezeslami, and Sarah Burl
“Improving the crystallization process for optimal drug development.”
American Laboratory. March 28, 2014.

Ahmed Awad, Michael J Collazo, Kate Carpio, Christina Flores, and Thomas C Bruice
“A convenient synthesis of the cytidyl 3′-terminal monomer for solid-phase synthesis of RNG oligonucleotides.”
Tetrahedron Letters. Vol. 53 No. 29 2012 Jul 18, 2012. 3792–3794


Crystal structure of the Shr Hemoglobin Interacting Domain 2 (2018)

Structure of NNQQNY from yeast prion Sup35 with zinc acetate determined by MicroED (2016)

Structure of NNQQNY from yeast prion Sup35 with cadmium acetate determined by MicroED (2016)

Structure of GNNQQNY from yeast prion Sup35 in space group P21 determined by MicroED (2016)

Structure of GNNQQNY from yeast prion Sup35 in space group P212121 determined by MicroED (2016)

Crystal structure of rescued two-component self-assembling tetrahedral cage T33-31 (2015)

Crystal Structure of Proteinase K from Engyodontium albuminhibited by METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE at 1.15 A resolution (2015)

Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (apo form) (2014)

Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (Mevalonate Bound) (2014)

Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (Mevalonate 3-Phosphate/ADP Bound) (2014)


Michael Collazo
(310) 882-2585
Boyer Hall 106, 611 Young Drive East, Los Angeles, CA 90095


Southern California Undergraduate Research Conference in Chemistry and Biochemistry, “A convenient synthesis of the cytidyl 3’-terminal monomer for solid-phase synthesis of RNG oligonucleotides,” April 2012.

Society for Advancing Chicanos and Native Americans in the Sciences (SACNAS) Conference and Iowa State University REU poster session, “Invertebrate diversity and abundance: indicators of urban stream condition in central Iowa,” Oct 2011 and Jun 2011.

UC Santa Barbara REU intern presentations and SACNAS Conference, “Pollen limitation, abortion rates, and the evolution of selfing in Clarkia unguiculata,” Aug 2010 and Oct 2010.

CSU Channel Islands REU poster session, “Determining the stability of CuSF protein by C-terminal truncation via induced mutagenesis,” Jun 2010.

CSU Channel Islands REU poster session, “Aerial arthropod productivity: developing indicators of salt marsh functioning at Ormond Beach, Ventura County, California,” Jun 2009.

Science Technology Engineering and Mathematics Center at Oxnard College, grand opening “The effect of salinity on the rooting, growth and survival of Frankenia grandiflora, Jaumea carnosa, and Sueda californica,” Dec 2008.

SAGE Faculty Research Forum, in recognition of outstanding research in the area of chemistry, May 2012.