Finer Structure of α-Synuclein, Aβ Fibrils determined (Eisenberg's Lab)


Diffusion accessibility as a method for visualizing macromolecular surface geometry (Yeates Lab)


Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly (Egea Lab)

Division of Microbial Genomics and Proteomics

Unicellular organisms account for a substantial fraction of global primary productivity. They represent the most evolutionarily and metabolically diverse organisms, with capacity to thrive in highly specialized environmental niches. In this Division, we apply emerging technologies to define and probe the genomes, proteomes and metabolism of prokaryotic and eukaryotic microbes. Our research efforts emphasize genome-level interpretations, especially in the context of the environment and in relation to other species, and offer a substantial component of discovery in uncharted metabolic pathways.

Division of Systems Biology and Design

Biological systems are distinguished by their high level of organization. Their composition from multiple interacting components allows them to exhibit many kinds of complex behaviors, enabling chemical transformations and synthetic processes that are often tightly regulated and/or spatially controlled for optimal performance. In this Division, we apply emerging technologies to dissect and re-engineer complex biochemical processes and structures. Our efforts aim to create advanced chemicals and novel biologically-based materials in support of DOE interests in energy, green chemistry, and bioprocessing.

Latest News

MBI Awards Dinner small

Professor David Eisenberg was awarded the Legacy Award at the 2nd Annual UCLA Molecular Biology Institute (MBI) Awards Dinner on November 12th.

The Legacy Award honors outstanding MBI faculty mentors who have worked to inspire, encourage and guide the next generation of scientists and thought leaders.Professor Eisenberg is a Distinguished Professor of Chemistry and Biochemistry and of Biological Chemistry, an HHMI investigator, and the inaugural Chair Holder of the Paul D. Boyer Professorship in Molecular Biology Biochemistry. […]

2015 Postdoctoral Awardees

Three Postdocs from MBI Labs were recipients of the 2015 Postdoc Awards. Crysten Blaby from the Merchant lab Luz Orozco from the Pellegrini lab Jose Rodriguez from the Eisenberg lab The events was held on Oct. 9th at the California NanoSystems Institute (CNSI). More information can be found here   Jose Rodriguez and Luz Orozco […]

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