January 29, 2006

Web Hosting Service

I am considering moving this blog to an external web server. If you know any good (and inexpensive) hosting service, please let me know. Thanks.

Posted by yxing at 01:49 PM | Comments (1)

January 25, 2006

Hearing silence

This is an excellent review by Laurence Hurst on selection at synonymous sites in mammals.

Posted by yxing at 09:46 AM | Comments (0)

January 24, 2006

Several Stem Cell Gene Expression Data-sets

Unique gene expression signatures of independently-derived human embryonic stem cell lines. Abeyta et.al., Human Molecular Genetics, 2004

Molecular signature of human embryonic stem cells and its comparison with the mouse. Sato et.al., Developmental Biology, 2003

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells. Boyer et.al., Cell, 2005

Transcriptome Profiling of Human and Murine ESCs Identifies Divergent Paths Required to Maintain the Stem Cell State. Wei et.al., Stem Cells, 2005

Posted by yxing at 10:25 PM | Comments (1)

Alternative transcript diversity symposium II

Click here for details.

Posted by yxing at 02:32 PM | Comments (0)

January 23, 2006

Aging and Gene Expression in the Primate Brain

See the article

Posted by yxing at 11:21 PM | Comments (0)

January 19, 2006

What fractions of human diseases are caused by splicing defect?

A very provocative question. Still don't know what's the best way to address it.

Posted by yxing at 01:14 AM | Comments (0)

January 13, 2006

several conferences of 2006

8th international bioinformatics conference 2006 Denmark
Quantitative Approaches to Gene Regulatory Systems San Diego,CA

Posted by yxing at 09:04 PM | Comments (0)

January 11, 2006

Alternative splicing vs gene duplication

gene duplication after alternative splicing.
Alternative splicing and gene duplication are inversely correlated evolutionary mechanisms.

Posted by yxing at 01:24 AM | Comments (0)

January 10, 2006

RNA selection pressure & Ka/Ks

Download the Preprint

Posted by yxing at 08:58 PM | Comments (0)

January 06, 2006

Why genes in pieces

This is a remarkable piece about splicing and alternative splicing, written by Walter Gilbert in 1977. Many of the exciting things we learn about alternative splicing using genomic data have been envisioned by this article, shortly after the phenomenon of splicing was discovered.

Posted by yxing at 06:46 PM | Comments (0)