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PHASER
 
PHASER
PHASER is a program for phasing macromolecular crystal structures with maximum likelihood methods. It has been developed by Randy Read's group at the University of Cambridge. It currently has methods for brute force and fast likelihood-based rotation and translation functions for molecular replacement. Methods for experimental phasing are under development.
Features

    * There is an automatic mode
    * Packing function
    * Anisotropy correction
    * Fast Rotation function
    * Fast Translation function
    * Brute Rotation function
    * Brute Translation function


PHASER runs on Linux machines s; the executable is:
/joule2/programs/lx_bin/phaser or just type "phaser"

The program is installed in /joule2/programs/phaser/phaser-linux-1.3.1:

The documentation is available from http://www-structmed.cimr.cam.ac.uk/phaser/documentation/phaser-1.3.html

The program is available from http://www-structmed.cimr.cam.ac.uk/phaser/

There is a tutorial at: http://www-structmed.cimr.cam.ac.uk/phaser/tutorial/keyword_tutorial.html

Reference:
Acta Cryst. (2004). D60, 432-438. Likelihood-enhanced fast rotation functions. L. C. Storoni, A. J. McCoy and R. J. Read

Example command file for automatic molecular replacement:
#!/bin/csh -f
phaser << eof
MODE MR_AUTO

HKLIN toxd.mtz
LABIN F = FTOXD3 SIGF = SIGFTOXD3

ENSEMBLE toxd PDBFilE 1D0D_B.pdb IDENTITY 0.364
COMPOSITION PROTEIN MW 7139 NUM 1
SEARCH ENSEMBLE toxd NUM 1

ROOT AUTO_toxd1

eof