Stress induced genes / proteins in Mycobacterium tuberculosis
Mycobacterium tuberculosis proteins regulated in response to various stress conditions were identified by transciptome and proteome analysis.

Study Name	Study Title	Reference
Hypoxia/NO
r00005	hypoxic response - microarray - Schoolnik	Sherman DR, Vos...
r00026	response to reduced oxygen - microarray - Stocker, Butcher, Marsh	Bacon J, James ...
r00027	adaptation to stationary phase and low-oxygen - genes induced during non-proliferating conditions - microarray - Schoolnik	Voskuil MI, Vis...
r00030	Genes up-regulated in anaerobic as compared to microaerophilic conditions - microarray - Parish	Muttucumaru DG,...
r00031	gene expression in non-replicating state - anerobic - microarray - Parish	Muttucumaru DG,...
p00002	protein response to low oxygen - proteomics - Berry and Andersen	Rosenkrands I, ...
p00004	proteins induced in anerobic versus aerobic conditions - proteomics - Akerlund	Starck J, Kalle...
r00050	Genes up-regulated in microaerophilic conditions - microarray - Parish	Muttucumaru DG,...
r00051	Genes up-regulated in anerobic conditions - microarray - Parish	Muttucumaru DG,...
r00006	Inhibition of respiration and growth by NO - microarray - Schoolnik	Voskuil MI, Sch...
r00015	effect of NO on gene expression -upregulated proteins - microarray - Jacobs and Chan	Ohno H, Zhu G, ...
r00016	effect of NO on gene expression - downregulated proteins - microarray - Jacobs and Chan	Ohno H, Zhu G, ...
Nutrition Starvation
r00008	nutrition starvation (4h) upregulated genes - microarray - Duncan	Betts JC, Lukey...
r00009	nutrition starvation (24h) - upregulated genes - microarray - Duncan	Betts JC, Lukey...
r00010	nutrition starvation (96h) upregulated genes - microarray - Duncan	Betts JC, Lukey...
r00011	nutrition starvation (4h) downregulated genes - microarray - Duncan	Betts JC, Lukey...
r00012	nutrition starvation (24h) upregulated genes - microarray - Duncan	Betts JC, Lukey...
r00032	genexpression following progressive nutritions starvations - Marsh and Butcher	Hampshire T, So...
p00003	nutrition starvation response - proteomics - Duncan	Betts JC, Lukey...
Acidic pH
r00019	acidic pH upregulated genes - microarray - Shinnick	Fisher MA, Plik...
r00020	acid pH downregulated genes - microarray - Shinnick	Fisher MA, Plik...
Heat Shock
r00024	gene expression in response heat shock - DnaK regulon -mircroarray - Young and Butcher	Stewart GR, Wer...
r00025	gene expression in response heat shock - DnaK and GroE regulon -mircroarray - Young and Butcher	Stewart GR, Wer...
r00049	100 heat shock proteins identified in the DnaK / GroE regulon study - mircroarray - Young and Butcher	Stewart GR, Wer...
r00047	upregulated genes in response to overexpression of the heat shock protein DnaJ microarray - Young	Stewart GR, Rob...
r00048	downregulated genes in response to overexpression of the heat shock protein DnaJ microarray - Young	Stewart GR, Rob...
Hydrogen Peroxide
r00028	upregulated genes in the presence of H2O2	Schnappinger D,...
r00034	downregulated genes in the presence of H2O2	Schnappinger D,...
Other
r00005	hypoxic response - microarray - Schoolnik	Sherman DR, Vos...
r00006	Inhibition of respiration and growth by NO - microarray - Schoolnik	Voskuil MI, Sch...
r00015	effect of NO on gene expression -upregulated proteins - microarray - Jacobs and Chan	Ohno H, Zhu G, ...
r00016	effect of NO on gene expression - downregulated proteins - microarray - Jacobs and Chan	Ohno H, Zhu G, ...
r00026	response to reduced oxygen - microarray - Stocker, Butcher, Marsh	Bacon J, James ...
r00027	adaptation to stationary phase and low-oxygen - genes induced during non-proliferating conditions - microarray - Schoolnik	Voskuil MI, Vis...
r00030	Genes up-regulated in anaerobic as compared to microaerophilic conditions - microarray - Parish	Muttucumaru DG,...
r00031	gene expression in non-replicating state - anerobic - microarray - Parish	Muttucumaru DG,...
p00002	protein response to low oxygen - proteomics - Berry and Andersen	Rosenkrands I, ...
p00004	proteins induced in anerobic versus aerobic conditions - proteomics - Akerlund	Starck J, Kalle...
r00050	Genes up-regulated in microaerophilic conditions - microarray - Parish	Muttucumaru DG,...
r00051	Genes up-regulated in anerobic conditions - microarray - Parish	Muttucumaru DG,...
r00013	nutrition starvation (96h) upregulated genes - microarray - Duncan	Betts JC, Lukey...

Access the regulated proteins/genes via the study name. In the dataset acccess the Mycobacterium tuberculosis Structural Genomics Database entry via the Rv-number and the computational linkages in the Prolinks Database via the gene name. Go Back to Main Page