Welcome to the UCLA-DOE FOLD Server (Version 4.0, upgraded December 10th, 2002).

The former server was based upon a method known as Sequence Derived Properties (SDP) as described by (Fischer and Eisenberg, 1997). The current server uses a several stage procedure to assign a structure to your sequence:

1. BLAST is used to check for obviously homologous sequences within the PDB.
2. If BLAST fails, iterative PSI-BLAST is employed.
3. If BLAST and PSI-BLAST are unsucessful, then the PSI-BLAST results are fed to PSI-PRED for secondary structure prediction.
4. The secondary structure prediction is used in conjunction with SDP.
5. Finally, if SDP is unable to find a strong match, our new method, DASEY (Mallick, Weiss, Eisenberg, 2002), is used.

To use this server, you must create a login and password (free). The results are stored on our server for 1 month. Please email me with any questions you may have.