DNA recognition by GAL4: structure of a protein-DNA complex


by Joe and Jill

Introduction:
The DNA-binding protein BLAH ...... the button will show protein in color and DNA in white at the N-terminus , Second Button and an Third button This button will animate the molecule. CONCLUSIONS
In summary the cyrstal structure shows that XXX binds to YYY
1. Specificty for the conserved CCG triplets, provided by the zinc-binding DNA recognition module in the major groove
2. Requirement for a symmetrical site, provided by coiled coil dimerization region that lies over the minor groove
3. Preference for the number of intervening base pairs, provided by the conformation of the linker.

References Spear Brittney, Michael Jackson . TITLE HERE. 2006 3000-3006