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PresenterDateTitle
Anni ZhaoFeb 13th, 2012Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory. Cell. 2012 Feb 3;148(3):515-29..
Jiyong ParkJan 30th, 2012Mechanisms of protein oligomerization: Inhibitor of functional amyloids templates a-synuclein fibrilla-tion. J Am Chem Soc. 2012 Jan 19. [Epub ahead of print].
Jung Reem WooDec 12th, 2011Functional links between aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science. 2011 Dec 2;334(6060):1241-5. .
Boris BrumshteinNov 28th, 2011Temperature-scan cryocrystallography reveals reaction intermediates in bacteriophytochrome. Nature. 2011 Oct 16;479(7373):428-32 .
Linda MiallauOct 3rd, 2011Structure of the Adenosine A(2A) Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine. Structure. 2011 Sep 7;19(9):1283-93..
Dan LiSep 19th, 2011A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca(2+)/Calmodulin- Dependent Kinase II Holoenzyme. Cell. 2011 Sep 2;146(5):732-45..
Michael ThompsonAug 29th, 2011Generation of protein lattices by fusing proteins with matching rotational symmetry. Nat Nanotechnol. 2011.
Natalie AndersonAug 22nd, 2011Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. NATURE | VOL 476 | 11 AUGUST 2011.
Nicole WheatleyAug 8th, 2011Quantitation of protein–protein interactions by thermal stability shift analysis. Protein Science 20(8) 2011 .
Lin JiangAug 1st, 2011Sequence and Structural Convergence of Broad and Potent HIV Antibodies. Science. 2011 Jul 14. [Epub ahead of print] That Mimic CD4 Binding. .
Andrew MinJul 25th, 2011A two-step chemical mechanism for ribosome-catalysed peptide bond formation. Nature. 2011 Jul 17. doi: 10.1038/nature10248. [Epub ahead of print].
Stuart SieversJul 18th, 2011Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP. Nature. 2011 Jul 6 [Epub ahead of print].
Meytal LandauJun 27th, 2011Latent TGF-β structure and activation. Nature. 16 June 2011; 474:343–349.
Fang ShengJun 20th, 2011A bacterium that can grow by using arsenic instead of phosphorus. Science. 2011 Jun 3;332(6034):1163-6. .
Riki StevensonJun 13th, 2011Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins. Nat Struct Mol Biol. 2011 Jun;18(6):693-700.
Minglei ZhaoMay 23rd, 2011Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin. Science 13 May 2011: Vol. 332 no. 6031 pp. 816-821 .
Heather McFarlaneMay 16th, 2011Crystal structure of oxygen-evolving photosystem II at a resolution of 1.9 Å. Nature 473: 55–60 (05 May 2011).
Jiyong ParkMay 9th, 2011Natural tri- to hexapeptides self-assemble in water to amyloid beta-type fiber aggregates by unexpected alpha-helical intermediate structures. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1361-6..
Howard ChangMay 2nd, 2011A universal method for detection of amyloidogenic misfolded proteins. Biochemistry, Just Accepted Manuscript.
Michael SawayaApr 25th, 2011Femtosecond X-ray protein nanocrystallography..
Angela SoriagaApr 18th, 2011Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan.
Boris BrumshteinApr 11th, 2011Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme..
Linda MiallauMar 21st, 2011Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation..
Cong LiuMar 14th, 2011Genetic selection designed to stabilize proteins uncovers a chaperone called Spy.
Arthur LaganowskyMar 7th, 2011Prion propagation and toxicity in vivo occur in two distinct mechanistic phases.
Sophia TsaiFeb 21st, 2011Development of an artificial cell, from self- organization to computation and self-reproduction.
Dan LiFeb 14th, 2011Directed evolution of a protein container..
Angela SoriagaFeb 7th, 2011X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel..
Heather McFarlaneOct 11th, 2010An unprecedented nucleic acid capture mechanism for excision of DNA damage. Nature 2010.
Minglei ZhaoOct 4th, 2010Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers. Nat Struct Mol Biol. 2010 Sep;17(9):1037-42..
Arturo Medrano-SotoSep 27th, 2010Predicting protein-protein interactions in the context of protein evolution. Mol Biosyst. 2010 Jan;6(1):55-64. .
Jiyong ParkSep 20th, 2010Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature 2010 Sep9; 467 (7312): 179-84.
James StroudSep 6th, 2010Atomic structure of human adenovirus by cryo-EM reveals interactions among protein networks. Science. 2010 Aug 27;329(5995):1038-43..
Anni ZhaoAug 30th, 2010Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans. PLoS Biol. 2010 Aug 10;8(8)..
Michael SawayaAug 23rd, 2010Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01. Science. 2010 Aug 13;329(5993):811-7. .
Boris BrumshteinAug 16th, 2010Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 2010 Aug 5;466(7307):774-8..
Lukasz SalwinskiJul 26th, 2010 An analytical solution to the kinetics of breakable filament assembly. Science. 2009 Dec 11;326(5959):1533-7..
Meytal LandauJul 19th, 2010Allostery and Intrinsic Disorder Mediate Transcription Regulation by Conditional Cooperativity. Cell 9 July 2010, 142(1): 101-111 .
Cong LiuJun 28th, 2010Protein refolding is required for assembly of the type three secretion needle. Nat Struct Mol Biol. 2010 Jun 13. .
Dan LiMay 24th, 2010Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature. 2010 May 13;465(7295):236-8..
Marcin ApostolMay 17th, 2010D-amino acids trigger biofilm disassembly Science. 2010 Apr 30;328(5978):627-9..
Jason ForseMay 10th, 2010Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1. Science. 2010 Apr 23;328(5977):470-3..
Magdalena IvanovaMay 3rd, 2010Super-resolution biomolecular crystallography with low-resolution data.Nature. 2010 Apr 22;464(7292):1218-22. .
Nina RamApr 26th, 2010Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology. Nature. 2010 Jan 28;463(7280):549-53..
Michael ThompsonApr 19th, 2010The structural basis of peptide-protein binding strategies. Structure. 2010 Feb 10;18(2):188-99..
Lin JiangApr 12th, 2010The structural basis of peptide-protein binding strategies. Structure. 2010 Feb 10;18(2):188-99..
Fang ShengMar 29th, 2010ttttttttttttttttttttttt.
Tobias SayreMar 22nd, 2010Spatially Ordered Dynamics of the Bacterial Carbon Fixation Machinery. Science, 5 March 2010, 1258-1261..
Lukasz GoldschmidtMar 15th, 2010Spatially Ordered Dynamics of the Bacterial Carbon Fixation Machinery. Science, 5 March 2010, 1258-1261..
Einat SprinzakMar 8th, 2010Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli. PLoS Biol. 2010 Feb 23;8(2):e1000317. .
Heather McFarlaneMar 1st, 2010Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome. Nature advance online publication 14 February 2010.
Minglei ZhaoFeb 22nd, 2010Aplysia CPEB Can Form Prion-like Multimers in Sensory Neurons that Contribute to Long-Term Facilitation. Cell, Volume 140, Issue 3, 421-435, 5 February 2010.
James StroudJan 11th, 2010Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature 462, 762-766 2009.
Anni ZhaoDec 14th, 2009Structural properties of pore-forming oligomers of alpha-synuclein..
Angela SoriagaDec 7th, 2009Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009 Nov 22. [Epub ahead of print].
Neil KingNov 23rd, 2009Direct inhibition of the NOTCH transcription factor complex. Nature. 2009 Nov 12;462(7270):182-8..
Howard ChangNov 16th, 2009Hemagglutinin Receptor Binding Avidity Drives Influenza A Virus Antigenic Drift. Science 30 October 2009: Vol. 326. no. 5953, pp. 734 - 736.
Christopher CrowleyNov 9th, 2009Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature. 2009 Oct 29;461(7268):1282-6..
Shiho TanakaNov 2nd, 2009The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA. Science. 2009 Oct 15. [Epub ahead of print].
Lukasz SalwinskiOct 26th, 2009Spatiotemporal control of cell signalling using a light-switchable protein interaction. Nature. 2009 Oct 15;461(7266):997-1001..
Linda MiallauOct 19th, 2009Gene therapy for red-green colour blindness in adult primates. ature. 2009 Sep 16. [Epub ahead of print].
Meytal LandauOct 5th, 2009Positive Selection of Tyrosine Loss in Metazoan Evolution. Science 25 September 2009: Vol. 325. no. 5948, pp. 1686 - 1688.
Cong LiuSep 28th, 2009Following evolutionary paths to protein-protein interactions with high affinity and selectivity. Nat Struct Mol Biol. 2009 Sep 13. [Epub ahead of print].
Arthur LaganowskySep 21st, 2009Promiscuous Substrate Recognition in Folding and Assembly Activities of the Trigger Factor Chaperone. Cell, Volume 138, Issue 5, 923-934, 4 September 2009 .
Dan LiSep 14th, 2009Myosin VI undergoes cargo-mediated dimerization. Cell. 2009 Aug 7;138(3):537-48..
Marcin ApostolAug 31st, 2009Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome. Science 2009 Aug 21;325(5943):966-70..
Richard LlewellynAug 24th, 2009The Secret Life of the Anthrax Agent Bacillus anthracis: Bacteriophage-Mediated Ecological Adaptations. PLoS One. 2009 Aug 12;4 (8) :e6532.
Jason ForseAug 17th, 2009Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nature Structural & Molecular Biology 16, 890 - 896 (2009) .
Stuart SieversAug 10th, 2009Synthetic protein scaffolds provide modular control over metabolic flux. Nature Biotechnology Published online: 2 August 2009.
Magdalena IvanovaAug 3rd, 2009Helical extension of the neuronal SNARE complex into the membrane. Nature 460, 525-528 2009 .
Lukasz GoldschmidtJul 27th, 2009Motif-directed flexible backbone design of functional interactions. Protein Sci. 2009 Jun;18(6):1293-305..
Stuart SieversJul 20th, 2009structure of a prokaryotic virtual proton pump at 3.2 angstrom resolution. Nature advance online publication 5 july 2009.
Arturo Medrano-SotoJun 29th, 2009X-Ray Structures of the Hexameric Building Block of the HIV Capsid.
Minglei ZhaoJun 29th, 2009Diversity and Complexity in DNA Recognition by Transcription Factors. Science Epub ahead of print.
Poh TengJun 8th, 2009Fabricating genetically engineered high-power lithium-ion batteries using multiple virus genes. Science. 2009 May 22;324(5930):1051-5. .
Jiyong ParkMay 25th, 2009Branching in amyloid fibril growth. Biophys J. 2009 Feb 18;96(4):1529-36..
Yingssu TsaiMay 18th, 2009Structural studies of the giant mimivirus. PLoS Biol. 2009 Apr 28;7(4):e92..
James StroudMay 11th, 2009A C. elegans LSD1 demethylase contributes to germline immortality by reprogramming epigenetic memory. Cell 2009 Apr 17;137(2):308-20..
Anni ZhaoMay 4th, 2009Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nature Structural & Molecular Biology 16, 380 - 389 (2009) .
Angela SoriagaApr 20th, 2009Coding-sequence determinants of gene expression in Escherichia coli. Science 2009 Apr 10;324(5924):255-8..
Michael SawayaApr 13th, 2009Structure of the connexin 26 gap junction channel at 3.5 A resolution. Nature 2009.
Howard ChangMar 30th, 2009Design and engineering of an O(2) transport protein. Nature 2009 Mar 19;458(7236):305-9..
Cong LiuMar 23rd, 2009Interprotofilament interactions between Alzheimer's A{beta}1-42 peptides in amyloid fibrils revealed by cryoEM. PNAS 2009 Mar 5. [Epub ahead of print].
Shiho TanakaMar 16th, 2009Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. PNAS 2009 Mar 3;106(9):3059-64. .
Lukasz SalwinskiMar 9th, 2009A hierarchical model for evolution of 23S ribosomal RNA. Nature 2009 457(7232):977-80. .
Christopher CrowleyMar 2nd, 2009Transmembrane passage of hydrophobic compounds through a protein channel wall. Nature 2009 Feb 1. [Epub ahead of print].
Dan LiFeb 9th, 2009Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB. Science Vol. 323. no. 5912, pp. 396 - 401.
Jason ForseJan 12th, 2009Quality control by the ribosome following peptide bond formation. Nature 457, 161-166 (8 January 2009).
Richard LlewellynJan 5th, 2009Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity. Cell, Volume 135, Issue 6, 12 December 2008, Pages 1085-1097 .
Richard LlewellynDec 22nd, 2008Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity. Cell, Volume 135, Issue 6, 12 December 2008, Pages 1085-1097 .
Magdalena IvanovaDec 15th, 2008Initiation and elongation in fibrillation of ALS-linked superoxide dismutase. PNAS December 2, 2008 vol. 105 .
Heather McFarlaneDec 8th, 2008Molecular structural basis for polymorphism in Alzheimer's β-amyloid fibrils. PNAS 2008 105:18349-18354.
Markus KaufmannDec 1st, 2008The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist. Science 322 no. 5905, pp. 1211 - 1217 2008 .
Jiyong ParkNov 24th, 2008A Molecular Dynamics Study of the Interaction of d-Peptide Amyloid Inhibitors with Their Target Sequence Reveals a Potential Inhibitory Pharmacophore Conformation. J Mol Biol. 2008 Oct 31;383(1):266-80 .
Lukasz GoldschmidtNov 17th, 2008Fragment-HMM: A new approach to protein structure prediction. Protein Science (2008), 17:1925-1934. .
Stuart SieversNov 10th, 2008Interactions between Hsp70 and the Hydrophobic Core of alpha-Synuclein Inhibit Fibril Assembly. ASAP Biochemistry. Web Release Date: November 1, 2008 .
Einat SprinzakNov 3rd, 2008Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy. Science 2008 Oct 9. [Epub ahead of print] Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy. Science 2008 .
Minglei ZhaoOct 27th, 2008Surface sites for engineering allosteric control in proteins. Science. 2008 Oct 17;322(5900):438-42..
Angela SoriagaOct 20th, 2008Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines (PNAS, 7 Oct 2008, 105:15334).
Arturo Medrano-SotoOct 13th, 2008Evolutionarily conserved substrate substructures for automated annotation of enzyme superfamilies (PLoS Comput. Biol, 1 Aug 2008, 4:e1000142).
Anni ZhaoOct 6th, 2008A regulatable switch mediates self-association in an immunoglobulin fold (NSMB, Sept. 2008, 15:965).
Jed WiltziusSep 29th, 2008Metabolic engineering of a thermophilic bacterium to produce ethanol at high yield (PNAS, 16 Sept 2008, 105:13769).
Arthur LaganowskySep 22nd, 2008Chemical and biological approaches synergize to ameliorate protein-folding diseases (Cell, 5 Sept 2008, 134:769) .
Yingssu TsaiSep 8th, 2008Evolutionary ecology of pungency in wild chilies (PNAS, 19 Aug 2008, 105:11808).
James StroudAug 25th, 2008Secreted transcription factor controls Mycobacterium tuberculosis virulence (Nature, 7 Aug 2008, 454:717).
James StroudAug 18th, 2008Secreted transcription factor controls Mycobacterium tuberculosis virulence (Nature, 7 Aug 2008, 454:717).
Michael SawayaAug 11th, 2008Crystal structure of the termination module of a nonribosomal peptide synthetase (Science, 1 Aug 2008, 321:659).
Shiho TanakaAug 4th, 20081. Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspFU (Nature, AOP 23 July 2008); 2.enterohaemorrhagic E. coli effector EspFU (Nature, AOP 23 July 2008); 2. The pathogen protein EspFU hijacks actin polymerization using mimicry and multivalency (Nature, AOP 23 July 2008) .
Howard ChangJul 28th, 2008Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT (Nat. Struct. Molec. Biol., July 2008, 15:746).
Neil KingJul 21st, 2008Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor (Nature, 10 July 2008, 454:177).
Meytal LandauJul 14th, 2008Structural basis of a potent peptide inhibitor designed for Kv1.3 channel, a therapeutic target of autoimmune disease (JBC, 4 July 2008, 283:19058).
Lukasz SalwinskiJul 7th, 2008Functional maps of protein complexes from quantitative genetic interaction data (PLoS Comput. Biol., April 2008, 4(4):e1000065).
Christopher CrowleyJun 30th, 2008Assembly reflects evolution of protein complexes (Nature, Advance Online Publication, 18 June 2008).
Marcin ApostolJun 23rd, 2008Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution (Science, 13 June 2008, 320: 1471).
Christopher MillerJun 16th, 2008Predictive behavior within microbial genetic networks (Science, 6 June 2008, 320:1313).
Jason ForseJun 9th, 2008Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins (PNAS, 3 June 2008, 105:7702); Structural basis for the regulated protease and chaperone function of DegP (Nature, advance online publication 21 May 2008).
Magdalena IvanovaMay 19th, 2008Genome analysis of the platypus reveals unique signatures of evolution (Nature, 8 May 2008, 453:175).
Heather McFarlaneMay 12th, 2008Design of protein function leaps by directed domain interface evolution (PNAS, 6 May 2008, 105(18): 6578).
Lukasz GoldschmidtMay 5th, 2008Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane (PNAS, 22 April 2008, 105(16): 6033).
Markus KaufmannApr 28th, 2008Bacteria subsisting on antibiotics (Science 4 April 2008: 100-103).
Linda MiallauApr 21st, 2008Opening and closing of the periplasmic gate in lactose permease (PNAS, 11 Mar 2008, 105:3774-8).
Toni LeeApr 7th, 2008Kemp elimination catalysts by computational enzyme design (Nature, advance online publication 19 March 2008).
Richard LlewellynMar 31st, 2008Two Seemingly Homologous Noncoding RNAs Act Hierarchically to Activate glmS mRNA Translation (PLoS Biology, March 2008, 6(3): e6).
Einat SprinzakMar 17th, 2008Intrinsically disordered proteins display no preference for chaperone binding in vivo. (PLoS Comp. Biol. Feb 2008).
Minglei ZhaoMar 10th, 2008A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing (Nature, 6 Mar 2008, 452:108).
Arturo Medrano-SotoMar 3rd, 2008Genome-wide experimental determination of barriers to horizontal gene transfer (Science, 30 Nov 2007, 318:1449).
Arthur LaganowskyFeb 25th, 2008Structural basis for the function and inhibition of an influenza virus proton channel (Nature, 31 Jan 2008, 451:596), Structure and mechanism of the M2 proton channel of influenza A virus (Nature, 31 Jan 2008, 451:591).
Yingssu TsaiFeb 4th, 2008Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages (PNAS, 22 Jan 2008, 105:1009).
Jed WiltziusJan 28th, 2008Designed protein-protein association (Science, 11 Jan 2008, 319:206).
James StroudJan 14th, 2008Host genome surveillance for retrotransposons by transposon-derived proteins (Nature, 19 Dec 2007, epub ahead of print).
Michael SawayaJan 7th, 2008Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin (Science, 2007 Dec 6, epub ahead of print).
Poh TengDec 17th, 2007Conformational reorganization of the SARS coronavirus spike following receptor binding: implications for membrane fusion (PLoS ONE, 2007 Oct 24, 2:e1082).
Jacques-Philippe ColletierDec 3rd, 2007A hierarchy of timescales in protein dynamics is linked to enzyme catalysis.
Neil KingNov 5th, 2007GPCR engineering yields high-resolution structural insights into beta2 adrenergic receptor function. (Science, published online 25 Oct 2007).
Jason ForseOct 29th, 2007High-resolution structure prediction and the crystallographic phase problem (Nature, 14 Oct 2007, advance online publication).
Meytal LandauOct 22nd, 2007A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice.
Magdalena IvanovaOct 1st, 2007Structure of acid-sensing ion channel 1 at 1.9 Ã… resolution and low pH (Nature, 20 Sept 2007, 449:316-323).
Christopher MillerSep 24th, 2007Crystal structure of an ancient protein: evolution by conformational epistasis (Science, 14 Sept 2007, 317:1544).
Rebecca NelsonSep 17th, 2007LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake (Science, 7 Sept 2007, 317:1390).
Marcin ApostolAug 27th, 2007Structure and function of an essential component of the outer membrane protein assembly machine (Science, 17 Aug 2007, 317:961); Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily (Science, 17 Aug 2007, 317:957).
Christopher CrowleyAug 20th, 2007Global changes to the ubiqutin system in Huntington's disease Nature 448, 704-708.
Lukasz GoldschmidtAug 13th, 2007A reversible wet/dry adhesive inspired by mussels and geckos (Nature, 19 July 2007, 448:338).
Huiying LiAug 6th, 2007Conformational entropy in molecular recognition by proteins (Nature, 19 July 2007, 448:325) .
Richard LlewellynJul 23rd, 2007Postreplicative formation of cohesion is required for repair and induced by a single DNA break (Science, 13 July 2007, 317:242).
Markus KaufmannJul 16th, 2007Host Resistance to Lung Infection Mediated by Major Vault Protein in Epithelial Cells Science 6 July 2007.
Howard ChangJul 9th, 2007Development of the Human Infant Intestinal Microbiota PLoS Biol. 2007 July 26; 5(7).
Linda MiallauJul 2nd, 2007Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS. EMBO advance online publication 14 June 2007.
Stuart SieversJun 25th, 2007Transvascular delivery of small interfering RNA to the central nervous system (Nature AOP, 17 June 2007).
Arturo Medrano-SotoJun 18th, 2007Probing transcription factor dynamics at the single-molecule level in a living cell (Science, 25 May 2007, 316:1191).
James StroudJun 11th, 2007In search of the biological significance of modular structures in protein networks (PLoS Comput. Biol., 1 Jun 2007, 3:e107).
Michael SawayaMay 28th, 2007Prion recognition elements govern nucleation, strain specificity and species barriers (Nature AOP, 9 May 2007).
Poh TengMay 14th, 2007Bacterial glycosidases for the production of universal red blood cells (Nat. Biotechnol., Apr 2007, 25:454).
Shiho TanakaMay 7th, 2007Expanding the diversity of chemical protein modification allows post-translational mimicry (Nature, 26 Apr 2007, 446:1105).
Jacques-Philippe ColletierApr 30th, 2007A toxic monomeric conformer of the polyglutamine protein (Nat. Struct. Mol. Biol., Apr 2007, 14:332).
Christopher MillerApr 9th, 2007CRISPR provides acquired resistance against viruses in prokaryotes (Science, 23 Mar 07, 315:1709).
Jason ForseMar 26th, 2007The crystal structure of a virus-like particle from the hyperthermohilic archaeon Pyrococcus furiosus provides insight into the evolution of viruses (JMB online, 3/5/07).
Lukasz SalwinskiMar 19th, 2007Structure of an ABC transporter in complex with its binding protein (Nature, 8 March 2007, 446:213).
Rebecca NelsonFeb 26th, 2007Global reconstruction of the human metabolic network based on genomic and bibliomic data (PNAS, 6 Feb 2007, 104:1777).
Einat SprinzakFeb 12th, 20071) Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation (Nat. Biotechnol., Jan 2007, 25:117); 2) Computational prediction of proteotypic peptides for quantitative proteomics (Nat. Biotechnol., Jan 2007, 25:125) .
Heather McFarlaneFeb 5th, 2007Protein and DNA sequence determinants of thermophilic adaptation (PLoS Comput. Biol., Jan 2007, 3:e5).
Lukasz GoldschmidtJan 29th, 2007All-atom ab initio folding of a diverse set of proteins (Structure, 17 Jan 2007, 15:53).
Jed WiltziusJan 22nd, 2007Antibacterial lysine analogs that target lysine riboswitches (Nat. Chem. Biol. 2007 Jan, 3:44).
Huiying LiJan 8th, 2007Variability and memory of protein levels in human cells (Nature 30 Nov 2006, 444:643).
Marcin ApostolDec 18th, 2006Enzyme-free nucleic acid logic circuits (Science 8 Dec 2006, 314:1585).
Richard LlewellynDec 11th, 2006Analyzing proteome topology and function by automated multidimensional fluorescence microscopy (Nature Biotechnology Oct 2006, 24:1270).
Markus KaufmannDec 4th, 2006Hot-spot mimicry of a cytokine receptor by a small molecule (PNAS 17 Oct 2006, 103:15422).
Arturo Medrano-SotoNov 27th, 2006The nature and dynamics of bacterial genomes (Science, 24 Mar 2006, 311:1730).
James StroudNov 20th, 2006Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). (Nature Genetics Nov 2006, 38:1348).
Stuart SieversNov 13th, 2006Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia (Nature AOP 1 November 2006).
Howard ChangNov 6th, 2006Symbiosis insights through metagenomic analysis of a microbial consortium (Nature 26 Oct 2006, 443:950).
Michael SawayaOct 16th, 2006Reassembly of shattered chromosomes in Deinococcus radiodurans (Nature AOP 27 Sept 2006).
Poh TengOct 9th, 2006Microdiesel: Escherichia coli engineered for fuel production. (Microbiology Sept 2006, 152:2529).
Morgan BeebyOct 2nd, 2006Mis-translation of a computationally designed protein yields an exceptionally stable homodimer: implications for protein engineering and evolution (JMB 6 Oct 2006, 362:1004).
Christopher MillerSep 25th, 2006A microrotary motor powered by bacteria (PNAS 12 Sept 2006, 103:13618).
Shiho TanakaSep 18th, 2006Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex (Nature 7 Sept 2006, 443:110).
Neil KingAug 14th, 2006Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions (Nat. Biotechnol. August 2006, 24:852).
Jason ForseAug 7th, 2006Protein flexibility acclimatizes photosynthetic energy conversion to the ambient temperature (Nature AOP, 23 July 2006).
Magdalena IvanovaJul 31st, 2006Atom-by-atom analysis of global downhill protein folding (Nature 20 July 2006, 442:317).
Lukasz SalwinskiJul 24th, 2006Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G (Science 14 July 2006, 313:187); Crystal structure of glycoprotein B from herpes simplex virus 1 (Science 14 July 2006, 313:217).
Heather McFarlaneJul 3rd, 2006Sequencing genomes from single cells by polymerase cloning (Nat Biotechnol 2006 June, 24:680).
Einat SprinzakJun 26th, 2006Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise (Nature 15 June 2006, 441:840).
Huiying LiMay 22nd, 2006Structure of the multidrug transporter EmrD from Escherichia coli (Science 5 May 2006, 312:741).
Marcin ApostolMay 8th, 2006Probing the conformation of the prion protein within a single amyloid fibril using a novel immunoconformational assay (J Biol Chem, published online ahead of print March 27, 2006, 10.1074/jbc.M601349200).
Markus KaufmannApr 10th, 2006High-sensitivity bacterial detection using biotin-tagged phage and quantum-dot nanocomplexes (PNAS 28 March 2006, 103:4841).
James StroudMar 27th, 2006A specific amyloid-beta protein asembly in the brain impairs memory..
Howard ChangMar 20th, 2006Genome-wide Detection of Polymorphisms at Nucleotide Resolution with a Single DNA Microarray.
Howard ChangMar 13th, 2006Designed divergent evolution of enzyme function.
Michael SawayaFeb 13th, 2006Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus (Nature 2006 Feb 2, 439:612).
Arturo Medrano-SotoFeb 6th, 2006Adaptive evolution of bacterial metabolic networks by horizontal gene transfer (Nature Genetics 2005 Dec, 37:1372).
Morgan BeebyJan 30th, 2006The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites (Cell 13 Jan 2006, 124:61).
Poh TengJan 16th, 2006.
Lukasz SalwinskiDec 5th, 2005Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gamma-c receptors.
Einat SprinzakNov 21st, 2005Oncogenic pathway signatures in human cancers as a guide to targeted therapies (Nature AOP, 6 Nov 2005).
Lukasz GoldschmidtOct 10th, 2005Crystallographic refinement by knowledge-based exploration of complex energy landscapes (Structure Sept 2005, 13:1311).
Daniel AndersonAug 8th, 2005Barker D, Pagel M (2005) Predicting Functional Gene Links from Phylogenetic-Statistical Analyses of Whole Genomes. PLoS Comp Biol 1(1): e3.
James StroudAug 1st, 2005Multiplexed detection of pathogen DNA with DNA-based fluorescence nanobarcodes (Nat. Biotechnol. Jul 2005, 23:885).
Howard ChangJul 25th, 2005Amyloid ion channels: A common structural link for protein-misfolding disease. Proc Natl Acad Sci U S A. 2005 Jul 14.
Huiying LiJun 6th, 2005Systematic interpretation of genetic interactions using protein networks (Nature Biotech. May 2005, 23:561).
Morgan BeebyMay 16th, 2005Computational thermostabilization of an enzyme. (Science 6 May 2005, 308:857).
Rebecca NelsonApr 4th, 2005Uncharged tRNA and Sensing of Amino Acid Deficiency in Mammalian Piriform Cortex (Science 18 March 2005, 307:1776).
Lukasz SalwinskiMar 28th, 2005Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis. Nature. 2005 Mar 24;434(7032):505-9. .
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Rebecca NelsonApr 2nd, 2001Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells .