Today: Tue, Nov 24 2009 [05:57] Back to current Journal Club listPrevious Journal Clubs| Presenter | Date | Title |
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| King,Neil | Nov 16, 2009 | Direct inhibition of the NOTCH transcription factor complex. Nature. 2009 Nov 12;462(7270):182-8.. | | Chang, Howard | Nov 9, 2009 | Hemagglutinin Receptor Binding Avidity Drives Influenza A Virus Antigenic Drift. Science 30 October 2009: Vol. 326. no. 5953, pp. 734 - 736. | | Crowley, Christopher | Nov 2, 2009 | Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature. 2009 Oct 29;461(7268):1282-6.. | | Tanaka, Shiho | Oct 26, 2009 | The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA. Science. 2009 Oct 15. [Epub ahead of print]. | | Salwinski, Lukasz | Oct 19, 2009 | Spatiotemporal control of cell signalling using a light-switchable protein interaction. Nature. 2009 Oct 15;461(7266):997-1001.. | | Miallau, Linda | Oct 5, 2009 | Gene therapy for red-green colour blindness in adult primates. Nature. 2009 Sep 16. [Epub ahead of print]. | | Landau, Meytal | Sep 28, 2009 | Positive Selection of Tyrosine Loss in Metazoan Evolution. Science 25 September 2009: Vol. 325. no. 5948, pp. 1686 - 1688. | | Liu, Cong | Sep 21, 2009 | Following evolutionary paths to protein-protein interactions with high affinity and selectivity. Nat Struct Mol Biol. 2009 Sep 13. [Epub ahead of print]. | | Laganowsky, Arthur | Sep 14, 2009 | Promiscuous Substrate Recognition in Folding and Assembly Activities of the Trigger Factor Chaperone. Cell, Volume 138, Issue 5, 923-934, 4 September 2009 . | | Li, Dan | Aug 31, 2009 | Myosin VI undergoes cargo-mediated dimerization. Cell. 2009 Aug 7;138(3):537-48.. | | Apostol, Marcin | Aug 24, 2009 | Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome. Science 2009 Aug 21;325(5943):966-70.. | | Llewellyn, Richard | Aug 17, 2009 | The Secret Life of the Anthrax Agent Bacillus anthracis: Bacteriophage-Mediated Ecological Adaptations. PLoS One. 2009 Aug 12;4 (8) :e6532. | | Forse, Jason | Aug 10, 2009 | Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nature Structural & Molecular Biology 16, 890 - 896 (2009) . | | Sievers, Stuart | Aug 3, 2009 | Synthetic protein scaffolds provide modular control over metabolic flux. Nature Biotechnology Published online: 2 August 2009. | | Ivanova,Magdalena | Jul 27, 2009 | Helical extension of the neuronal SNARE complex into the membrane. Nature 460, 525-528 2009 . | | Goldschmidt, Lukasz | Jul 20, 2009 | Motif-directed flexible backbone design of functional interactions. Protein Sci. 2009 Jun;18(6):1293-305.. | | Sievers, Stuart | Jul 13, 2009 | structure of a prokaryotic virtual proton pump at 3.2 angstrom resolution. Nature advance online publication 5 july 2009. | | Zhao, Minglei | Jun 22, 2009 | Diversity and Complexity in DNA Recognition by Transcription Factors. Science Epub ahead of print. | | Medrano-Soto, Arturo | Jun 15, 2009 | X-Ray Structures of the Hexameric Building Block of the HIV Capsid. | | Teng, Poh | Jun 1, 2009 | Fabricating genetically engineered high-power lithium-ion batteries using multiple virus genes. Science. 2009 May 22;324(5930):1051-5. . | | Park, Jiyong | May 18, 2009 | Branching in amyloid fibril growth. Biophys J. 2009 Feb 18;96(4):1529-36.. | | Tsai, Yingssu | May 11, 2009 | Structural studies of the giant mimivirus. PLoS Biol. 2009 Apr 28;7(4):e92.. | | Stroud, James | May 4, 2009 | A C. elegans LSD1 demethylase contributes to germline immortality by reprogramming epigenetic memory. Cell 2009 Apr 17;137(2):308-20.. | | Zhao, Anni | Apr 27, 2009 | Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nature Structural & Molecular Biology 16, 380 - 389 (2009) . | | Soriaga, Angela | Apr 13, 2009 | Coding-sequence determinants of gene expression in Escherichia coli. Science 2009 Apr 10;324(5924):255-8.. | | Sawaya, Michael | Apr 6, 2009 | Structure of the connexin 26 gap junction channel at 3.5 A resolution. Nature 2009. | | Chang, Howard | Mar 23, 2009 | Design and engineering of an O(2) transport protein. Nature 2009 Mar 19;458(7236):305-9.. | | Liu, Cong | Mar 16, 2009 | Interprotofilament interactions between Alzheimer's A{beta}1-42 peptides in amyloid fibrils revealed by cryoEM. PNAS 2009 Mar 5. [Epub ahead of print]. | | Tanaka, Shiho | Mar 9, 2009 | Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. PNAS 2009 Mar 3;106(9):3059-64. . | | Salwinski, Lukasz | Mar 2, 2009 | A hierarchical model for evolution of 23S ribosomal RNA. Nature 2009 457(7232):977-80. . | | Crowley, Christopher | Feb 23, 2009 | Transmembrane passage of hydrophobic compounds through a protein channel wall. Nature 2009 Feb 1. [Epub ahead of print]. | | President's Day Holiday - No meeting, | Feb 16, 2009 | Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation. J. Biol. Chem., Vol. 284, Issue 6, 3917-3924, 2009. | | Li, Dan | Feb 2, 2009 | Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB. Science Vol. 323. no. 5912, pp. 396 - 401. | | Martin Luther King Holiday - No meeting, | Jan 19, 2009 | High Functional Diversity in Mycobacterium tuberculosis Driven by Genetic Drift and Human Demography. PLoS Biol. 2008 Dec 16;6(12):e311.. | | Forse, Jason | Jan 5, 2009 | Quality control by the ribosome following peptide bond formation. Nature 457, 161-166 (8 January 2009). | | Llewellyn, Richard | Dec 15, 2008 | Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity. Cell, Volume 135, Issue 6, 12 December 2008, Pages 1085-1097 . | | Ivanova,Magdalena | Dec 8, 2008 | Initiation and elongation in fibrillation of ALS-linked superoxide dismutase. PNAS December 2, 2008 vol. 105 . | | McFarlane, Heather | Dec 1, 2008 | Molecular structural basis for polymorphism in Alzheimer's β-amyloid fibrils. PNAS 2008 105:18349-18354. | | Kaufmann, Markus | Nov 24, 2008 | The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist. Science 322 no. 5905, pp. 1211 - 1217 2008 . | | Park, Jiyong | Nov 17, 2008 | A Molecular Dynamics Study of the Interaction of d-Peptide Amyloid Inhibitors with Their Target Sequence Reveals a Potential Inhibitory Pharmacophore Conformation. J Mol Biol. 2008 Oct
31;383(1):266-80 . | | Goldschmidt, Lukasz | Nov 10, 2008 | Fragment-HMM: A new approach to protein structure prediction. Protein Science (2008), 17:1925-1934. . | | Sievers, Stuart | Nov 3, 2008 | Interactions between Hsp70 and the Hydrophobic Core of alpha-Synuclein Inhibit Fibril Assembly. ASAP Biochemistry. Web Release Date: November 1, 2008 . | | Sprinzak, Einat | Oct 27, 2008 | Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy. Science. 2008 Oct 9. [Epub ahead of print]. | | Zhao, Minglei | Oct 20, 2008 | Surface sites for engineering allosteric control in proteins. Science. 2008 Oct 17;322(5900):438-42.. | | Soriaga, Angela | Oct 13, 2008 | Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines (PNAS, 7 Oct 2008, 105:15334). | | Medrano-Soto, Arturo | Oct 6, 2008 | Evolutionarily conserved substrate substructures for automated annotation of enzyme superfamilies (PLoS Comput. Biol, 1 Aug 2008, 4:e1000142). | | Zhao,Anni | Sep 29, 2008 | A regulatable switch mediates self-association in an immunoglobulin fold (NSMB, Sept. 2008, 15:965). | | Wiltzius, Jed | Sep 22, 2008 | Metabolic engineering of a thermophilic bacterium to produce ethanol at high yield (PNAS, 16 Sept 2008, 105:13769). | | Laganowsky, Arthur | Sep 15, 2008 | Chemical and biological approaches synergize to ameliorate protein-folding diseases (Cell, 5 Sept 2008, 134:769) . | | Tsai, Yingssu | Aug 25, 2008 | Evolutionary ecology of pungency in wild chilies (PNAS, 19 Aug 2008, 105:11808). | | Stroud, James | Aug 11, 2008 | Secreted transcription factor controls Mycobacterium tuberculosis virulence (Nature, 7 Aug 2008, 454:717). | | Sawaya, Michael | Aug 4, 2008 | Crystal structure of the termination module of a nonribosomal peptide synthetase (Science, 1 Aug 2008, 321:659). | | Tanaka, Shiho | Jul 28, 2008 | 1. Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspFU (Nature, AOP 23 July 2008); 2. The pathogen protein EspFU hijacks actin polymerization using mimicry and multivalency (Nature, AOP 23 July 2008) . | | Chang, Howard | Jul 21, 2008 | Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT (Nat. Struct. Molec. Biol., July 2008, 15:746). | | King,Neil | Jul 14, 2008 | Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor (Nature, 10 July 2008, 454:177). | | Landau, Meytal | Jul 7, 2008 | Structural basis of a potent peptide inhibitor designed for Kv1.3 channel, a therapeutic target of autoimmune disease (JBC, 4 July 2008, 283:19058). | | Salwinski, Lukasz | Jun 30, 2008 | Functional maps of protein complexes from quantitative genetic interaction data (PLoS Comput. Biol., April 2008, 4(4):e1000065). | | Crowley, Christopher | Jun 23, 2008 | Assembly reflects evolution of protein complexes (Nature, 26 June 2008, 453:1262). | | Apostol, Marcin | Jun 16, 2008 | Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution (Science, 13 June 2008, 320: 1471). | | Miller, Christopher | Jun 9, 2008 | Predictive behavior within microbial genetic networks (Science, 6 June 2008, 320:1313). | | Crowley, Christopher | Jun 2, 2008 | Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins (PNAS, 3 June 2008, 105:7702); Structural basis for the regulated protease and chaperone function of DegP (Nature, advance online publication 21 May 2008). | | Ivanova,Magdalena | May 12, 2008 | Genome analysis of the platypus reveals unique signatures of evolution (Nature, 8 May 2008, 453:175). | | Kaufmann, Markus | Apr 21, 2008 | Bacteria subsisting on antibiotics (Science 4 April 2008: 100-103). | | Miallau, Linda | Apr 14, 2008 | Opening and closing of the periplasmic gate in lactose permease (PNAS, 11 Mar 2008, 105:3774-8). | | Lee, Toni | Mar 31, 2008 | Kemp elimination catalysts by computational enzyme design (Nature, advance online publication 19 March 2008). | | Llewellyn, Richard | Mar 24, 2008 | Two Seemingly Homologous Noncoding RNAs Act Hierarchically to Activate glmS mRNA Translation (PLoS Biology, March 2008, 6(3): e6). | | Sprinzak, Einat | Mar 10, 2008 | Intrinsically disordered proteins display no preference for chaperone binding in vivo. (PLoS Comp. Biol. Feb 2008). | | Zhao, Minglei | Mar 3, 2008 | A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing (Nature, 6 Mar 2008, 452:108). | | Medrano-Soto, Arturo | Feb 25, 2008 | Genome-wide experimental determination of barriers to horizontal gene transfer (Science, 30 Nov 2007, 318:1449). | | Laganowsky, Arthur | Feb 11, 2008 | Structural basis for the function and inhibition of an influenza virus proton channel (Nature, 31 Jan 2008, 451:596), Structure and mechanism of the M2 proton channel of influenza A virus (Nature, 31 Jan 2008, 451:591). | | Norcross, Todd | Feb 4, 2008 | Petri net-based method for the analysis of the dynamics of signal propagation in signalling pathways (Bioinformatics, 15 Jan 2008, 24:209). | | Tsai, Yingssu | Jan 28, 2008 | Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages (PNAS, 22 Jan 2008, 105:1009). | | Wiltzius, Jed | Jan 14, 2008 | Designed protein-protein association (Science, 11 Jan 2008, 319:206). | | Stroud, James | Jan 7, 2008 | Host genome surveillance for retrotransposons by transposon-derived proteins (Nature, 19 Dec 2007, epub ahead of print). | | Sawaya, Michael | Dec 17, 2007 | Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin (Science, 2007 Dec 6, epub ahead of print). | | Teng, Poh | Dec 10, 2007 | Conformational reorganization of the SARS coronavirus spike following receptor binding: implications for membrane fusion (PLoS ONE, 2007 Oct 24, 2:e1082). | | Colletier, Jacques-Philippe | Nov 26, 2007 | A hierarchy of timescales in protein dynamics is linked to enzyme catalysis. | | Cam Mura, guest speaker | Nov 19, 2007 | Cooperation and conflict in quorum-sensing bacterial populations (Nature, 15 Nov 2007, 450:411); a linear pentapeptide is a quorum-semsomg factor required for mazEF-mediated cell death in E. coli (Science, 26 Oct 2007, 318:652). | | King,Neil | Oct 29, 2007 | GPCR engineering yields high-resolution structural insights into beta2 adrenergic receptor function. (Science, published online 25 Oct 2007). | | Forse, Jason | Oct 22, 2007 | High-resolution structure prediction and the crystallographic phase problem (Nature, 14 Oct 2007, advance online publication). | | Landau, Meytal | Oct 15, 2007 | A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice. | | Ivanova,Magdalena | Sep 24, 2007 | Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH (Nature, 20 Sept 2007, 449:316-323). | | Miller, Christopher | Sep 17, 2007 | Crystal structure of an ancient protein: evolution by conformational epistasis (Science, 14 Sept 2007, 317:1544). | | Nelson, Rebecca | Sep 10, 2007 | LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake (Science, 7 Sept 2007, 317:1390). | | Labor Day, no meeting | Sep 3, 2007 | A common fold mediates vertebrate defense and bacterial attack (Science, published online 23 Aug 2007). | | Apostol, Marcin | Aug 20, 2007 | Structure and function of an essential component of the outer membrane protein assembly machine (Science, 17 Aug 2007, 317:961); Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily (Science, 17 Aug 2007, 317:957). | | Crowley, Christopher | Aug 13, 2007 | Global changes to the ubiqutin system in Huntington's disease Nature 448, 704-708. | | Goldshmidt, Lukasz | Aug 6, 2007 | A reversible wet/dry adhesive inspired by mussels and geckos (Nature, 19 July 2007, 448:338). | | Li, Huiying | Jul 23, 2007 | Conformational entropy in molecular recognition by proteins (Nature, 19 July 2007, 448:325) . | | Llewellyn, Richard | Jul 16, 2007 | Postreplicative formation of cohesion is required for repair and induced by a single DNA break (Science, 13 July 2007, 317:242). | | Kaufmann, Markus | Jul 9, 2007 | Host Resistance to Lung Infection Mediated by Major Vault Protein in Epithelial Cells Science 6 July 2007. | | Guo, Zhefeng | Jul 2, 2007 | Development of the Human Infant Intestinal Microbiota PLoS Biol. 2007 July 26; 5(7). | | Miallau, Linda | Jun 25, 2007 | Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS. EMBO advance online publication 14 June 2007. | | Sievers, Stuart | Jun 18, 2007 | Transvascular delivery of small interfering RNA to the central nervous system (Nature AOP, 17 June 2007). | | Medrano-Soto, Arturo | Jun 11, 2007 | Probing transcription factor dynamics at the single-molecule level in a living cell (Science, 25 May 2007, 316:1191). | | Stroud, James | Jun 4, 2007 | In search of the biological significance of modular structures in protein networks (PLoS Comput. Biol., 1 Jun 2007, 3:e107). | | Sawaya, Michael | May 21, 2007 | Prion recognition elements govern nucleation, strain specificity and species barriers (Nature AOP, 9 May 2007). | | Riley, Robert | May 14, 2007 | Stepwise formation of the bacterial flagellar system (PNAS, 24 Apr 2007, 104:7116). | | Teng, Poh | May 7, 2007 | Bacterial glycosidases for the production of universal red blood cells (Nat. Biotechnol., Apr 2007, 25:454). | | Tanaka, Shiho | Apr 30, 2007 | Expanding the diversity of chemical protein modification allows post-translational mimicry (Nature, 26 Apr 2007, 446:1105). | | Colletier, Jacques-Philippe | Apr 23, 2007 | A toxic monomeric conformer of the polyglutamine protein (Nat. Struct. Mol. Biol., Apr 2007, 14:332). | | Norcross, Todd | Apr 16, 2007 | Assessment of the probabilities for evolutionary structural changes in protein folds (Bioinformatics, advance access published 4 Feb 2007). | | Miller, Christopher | Apr 2, 2007 | CRISPR provides acquired resistance against viruses in prokaryotes (Science, 23 Mar 07, 315:1709). | | Forse, Jason | Mar 19, 2007 | The crystal structure of a virus-like particle from the hyperthermophilic archaeon Pyrococcus furiosus provides insight into the evolution of viruses (JMB online, 3/5/07). | | Salwinski, Lukasz | Mar 12, 2007 | Structure of an ABC transporter in complex with its binding protein (Nature, 8 March 2007, 446:213). | | Nelson, Rebecca | Feb 12, 2007 | Global reconstruction of the human metabolic network based on genomic and bibliomic data (PNAS, 6 Feb 2007, 104:1777). | | Sprinzak, Einat | Feb 5, 2007 | 1) Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation (Nat. Biotechnol., Jan 2007, 25:117); 2) Computational prediction of proteotypic peptides for quantitative proteomics (Nat. Biotechnol., Jan 2007, 25:125) . | | McFarlane, Heather | Jan 29, 2007 | Protein and DNA sequence determinants of thermophilic adaptation (PLoS Comput. Biol., Jan 2007, 3:e5). | | Goldshmidt, Lukasz | Jan 22, 2007 | All-atom ab initio folding of a diverse set of proteins (Structure, 17 Jan 2007, 15:53). | | Wiltzius, Jed | Jan 8, 2007 | Antibacterial lysine analogs that target lysine riboswitches (Nat. Chem. Biol. 2007 Jan, 3:44). | | Li, Huiying | Dec 18, 2006 | Variability and memory of protein levels in human cells (Nature 30 Nov 2006, 444:643). | | Apostol, Marcin | Dec 11, 2006 | Enzyme-free nucleic acid logic circuits (Science 8 Dec 2006, 314:1585). | | Llewellyn, Richard | Dec 4, 2006 | Analyzing proteome topology and function by automated multidimensional fluorescence microscopy (Nature Biotechnology Oct 2006, 24:1270). | | Kaufmann, Markus | Nov 27, 2006 | Hot-spot mimicry of a cytokine receptor by a small molecule (PNAS 17 Oct 2006, 103:15422). | | Medrano-Soto, Arturo | Nov 20, 2006 | The nature and dynamics of bacterial genomes (Science, 24 Mar 2006, 311:1730). | | Stroud, James | Nov 13, 2006 | Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). (Nature Genetics Nov 2006, 38:1348). | | Sievers, Stuart | Nov 6, 2006 | Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia (Nature AOP 1 November 2006). | | Guo, Zhefeng | Oct 30, 2006 | Symbiosis insights through metagenomic analysis of a microbial consortium (Nature 26 Oct 2006, 443:950). | | Sawaya, Michael | Oct 9, 2006 | Reassembly of shattered chromosomes in Deinococcus radiodurans (Nature AOP 27 Sept 2006). | | Teng, Poh | Oct 2, 2006 | Microdiesel: Escherichia coli engineered for fuel production. (Microbiology Sept 2006, 152:2529). | | Beeby, Morgan | Sep 25, 2006 | Mis-translation of a computationally designed protein yields an exceptionally stable homodimer: implications for protein engineering and evolution (JMB 6 Oct 2006, 362:1004). | | Miller, Christopher | Sep 18, 2006 | A microrotary motor powered by bacteria (PNAS 12 Sept 2006, 103:13618). | | Tanaka, Shiho | Sep 11, 2006 | Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex (Nature 7 Sept 2006, 443:110). | | Sambashivan, Shilpa | Aug 21, 2006 | Crystal structures of a multidrug transporter reveal a functionally rotating mechanism (Nature AOP, 16 August 2006). | | Riley, Robert | Aug 14, 2006 | DNA detection using recombination proteins (PLOS Biol July 2006, 4(7):e204). | | King, Neil | Aug 7, 2006 | Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions (Nat. Biotechnol. July 2006, 24:852). | | Forse, Jason | Jul 31, 2006 | Protein flexibility acclimatizes photosynthetic energy conversion to the ambient temperature (Nature AOP, 23 July 2006). | | Magdalena Ivanova, | Jul 24, 2006 | Atom-by-atom analysis of global downhill protein folding (Nature 20 July 2006, 442:317). | | Salwinski, Lukasz | Jul 17, 2006 | Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G (Science 14 July 2006, 313:187); Crystal structure of glycoprotein B from herpes simplex virus 1 (Science 14 July 2006, 313:217). | | McFarlane, Heather | Jun 26, 2006 | Sequencing genomes from single cells by polymerase cloning (Nat Biotechnol 2006 June, 24:680). | | Sprinzak, Einat | Jun 19, 2006 | Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise (Nature 15 June 2006, 441:840). | | Li, Huiying | May 8, 2006 | Structure of the multidrug transporter EmrD from Escherichia coli (Science 5 May 2006, 312:741). | | Apostol, Marcin | May 1, 2006 | Probing the conformation of the prion protein within a single amyloid fibril using a novel immunoconformational assay (J Biol Chem, published online ahead of print March 27, 2006, 10.1074/jbc.M601349200). | | O'Connor, Brian | Apr 24, 2006 | Deciphering the evolution and metaboism of an anammox bacterium from a community genome (Nature 6 Apr 2006, 440:790). | | Boutz, Daniel | Apr 17, 2006 | Protein stability promotes evolvability (PNAS 11 April 2006, 103: 5869) . | | Bowers, Peter | Apr 10, 2006 | . | | Kaufmann, Markus | Apr 3, 2006 | High-sensitivity bacterial detection using biotin-tagged phage and quantum-dot nanocomplexes (PNAS 28 March 2006, 103:4841). | | Stroud, James | Mar 20, 2006 | A specific amyloid-beta protein asembly in the brain impairs memory.. | | Guo, Zhefeng | Mar 6, 2006 | Genome-wide Detection of Polymorphisms at Nucleotide Resolution with a Single DNA Microarray. | | Banatao, Diosdado Rey | Feb 13, 2006 | Identification of protein domains by shotgun proteolysis (JMB in press: doi:10.1016/j.jmb.2006.01.057) . | | Sawaya, Michael | Feb 6, 2006 | Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus (Nature 2006 Feb 2, 439:612). | | Medrano-Soto, Arturo | Jan 30, 2006 | Adaptive evolution of bacterial metabolic networks by horizontal gene transfer (Nature Genetics 2005 Dec, 37:1372). | | Beeby, Morgan | Jan 23, 2006 | The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites (Cell 13 Jan 2006, 124:61). | | Teng, Poh | Jan 9, 2006 | . | | Salwinski, Lukasz | Nov 28, 2005 | Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gamma-c receptors. | | Sprinzak, Einat | Nov 14, 2005 | Oncogenic pathway signatures in human cancers as a guide to targeted therapies (Nature AOP, 6 Nov 2005). | | Wiltzius, Jed | Oct 10, 2005 | Oncogenic pathway signatures in human cancers as a guide to targeted therapies (Nature AOP, 6 Nov 2005). | | Goldshmidt, Lukasz | Oct 3, 2005 | Crystallographic refinement by knowledge-based exploration of complex energy landscapes (Structure Sept 2005, 13:1311). | | Norcross, Todd | Sep 26, 2005 | Using information theory to search for co-evolving residues in proteins (Bioinformatics, advance access 13 Sept 2005). | | Labor Day, no meeting | Sep 5, 2005 | A Strategy for Probing the Function of Noncoding RNAs Finds a Repressor of NFAT. Science, Vol 309, Issue 5740, 1570-1573. | | Bowers, Peter | Aug 15, 2005 | Structural basis for the activation of cholera toxin by human ARF6-GTP (Science 12 Aug 2005, 309:1093) . | | Chaudhuri, Barnali | Aug 8, 2005 | Global rigid body modeling of macromolecular complexes against small-angle scattering data. (Biophys. J. 2005, 89:1237) . | | Tsai, Yingssu | Aug 1, 2005 | Barker D, Pagel M (2005) Predicting Functional Gene Links from Phylogenetic-Statistical Analyses of Whole Genomes. PLoS Comp Biol 1(1): e3. | | Stroud, James | Jul 25, 2005 | Multiplexed detection of pathogen DNA with DNA-based fluorescence nanobarcodes (Nat. Biotechnol. Jul 2005, 23:885). | | Guo, Zhefeng | Jul 18, 2005 | Amyloid ion channels: A common structural link for protein-misfolding disease. Proc Natl Acad Sci U S A. 2005 Jul 14. | | Thompson, Michael | Jul 11, 2005 | X-ray structure of a tetranucleosome and its implications for the chromatin fibre. Schalch T, Duda S, Sargent DF, Richmond TJ. Nature. 2005 Jul 7;436(7047):138-41.. | | Li, Huiying | May 23, 2005 | Systematic interpretation of genetic interactions using protein networks (Nature Biotech. May 2005, 23:561). | | Banatao, Rey | May 16, 2005 | Programmable DNA self-assemblies for nanoscale organization of ligands and proteins. (Nano Lett. Apr 2005, 5:729). | | Beeby, Morgan | May 9, 2005 | Computational thermostabilization of an enzyme. (Science 6 May 2005, 308:857). | | Kim, Sul-Min | May 2, 2005 | Identification of a Multicomponent Complex required for Outer Membrane Biogenesis in E. Coli. | | Laidman, Janel | Apr 25, 2005 | The GB1 Amyloid Fibril: Recruitment of the Peripheral beta-Strands of the Domain Swapped Dimer into the Polymeric Interface. | | Ivanova, Magdalena | Apr 11, 2005 | Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins (Cell 8 April 2005, 121:49). | | Norcross, Todd | Apr 4, 2005 | Protein homology detection by HMM?HMM comparison (Bioinformatics 1 Apr 2005, 21:951). | | Nelson, Rebecca | Mar 28, 2005 | Uncharged tRNA and Sensing of Amino Acid Deficiency in Mammalian Piriform Cortex (Science 18 March 2005, 307:1776). | | Salwinski, Lukasz | Mar 14, 2005 | Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis. Nature. 2005 Mar 24;434(7032):505-9. . | | Riley, Robert | Mar 7, 2005 | Computational verification of protein-protein interactions by orthologous co-expression. (BMC Bioinformatics 2 Mar 2005, 6:40). | | Strong, Michael | Feb 28, 2005 | Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals (Nature, published online 27 Feb 2005). | | Sprinzak, Einat | Feb 14, 2005 | Highly conserved non-coding sequences are associated with vertebrate development. Woolfe A, Goodson M, Goode DK, Snell P, McEwen GK, Vavouri T, Smith SF, North P, Callaway H, Kelly K, Walter K, Abnizova I, Gilks W, Edwards YJ, Cooke JE, Elgar G. PLoS Biol. 2005 Jan;3(1):e7. Epub 2004 Nov 11.. | | Kaufmann, Markus | Jan 24, 2005 | Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils (Science 14 Jan 2005, 307:262). | | Boutz, Daniel | Jan 10, 2005 | Molecular basis for amyloid fibril formation and stability (PNAS 11 Jan 2005, 102:315). | | Chaudhuri, Barnali | Jan 3, 2005 | "Complementarity of Structure Ensembles in Protein-Protein Binding" Raik Gr?nberg1, Johan Leckner1, 2 and Michael Nilges Structure Volume 12, Issue 12 , December 2004, Pages 2125-2136 . | | Stroud, James | Dec 13, 2004 | Mitochondrial fission proteins regulate programmed cell death in yeast (Genes Dev. 15 Nov 2004, 18:2785). | | Guo, Zhefeng | Dec 6, 2004 | Human prion protein with valine 129 prevents expression of variant CJD phenotype. Science, 2004, 306:1793-1796. 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EMBO J. 2004 23: 4330-4341 . | | Li, Huiying | Oct 25, 2004 | A glycine-dependent riboswitch that uses cooperative binding to control gene expression (Science 8 Oct 2004, 306:275). | | Beeby, Morgan | Oct 18, 2004 | The site specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination (Nature Biotechnol. Oct 2004, 22(10):1297).. | | Kim, Sul-Min | Oct 11, 2004 | The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics (Nat. Struct. Mol. Biol. 2004, 11:963). | | Laidman, Janel | Oct 4, 2004 | "Trigger factor in complex with the ribosome forms a molecular cradle for nascent proteins" Nature 431 590-96. | | Bowers, Peter | Sep 27, 2004 | Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins (Nat. Biotechnol. 12 Sept 2004 - epub ahead of print). | | Miller, Christopher | Sep 20, 2004 | Genomic analysis of regulatory network dynamics reveals large topological changes. 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Griffith,Scott | May 17, 1999 | . | | Landgraf,Ralf | May 10, 1999 | . | | Xenarios,Ioannis | Apr 19, 1999 | . | | Pfluegl,Gaston | Apr 12, 1999 | . | | Valentine,Elizabeth | Mar 22, 1999 | . | | Balbirnie,Melinda | Mar 8, 1999 | . | | Eisenberg,David | Mar 1, 1999 | . | | Pellegrini,Matteo | Feb 15, 1999 | . | | Salwinski,Lukasz | Feb 8, 1999 | . | | Weiss,Bob | Feb 1, 1999 | . | | Pellegrini,Matteo | Jan 25, 1999 | . | | Dym,Orly | Jan 18, 1999 | . | | Mallick,Parag | Jan 11, 1999 | . | | Steere,Boyd | Nov 30, 1998 | . | | Grothe,Robert | Nov 23, 1998 | . | | Colovos,Chris | Nov 16, 1998 | . | | Marcotte,Edward | Nov 2, 1998 | . | | Pfluegl,Gaston | Oct 26, 1998 | . | | Serag,Ahmed | Oct 19, 1998 | . | | Griffith,Scott | Oct 12, 1998 | . | | Toth,Eric | Sep 21, 1998 | . | | Padilla,Jennifer | Sep 14, 1998 | . | | Ivanova,Magdalena | Aug 31, 1998 | . | | Fahrner,Rick | Aug 24, 1998 | . | | Gill,Harry | Aug 17, 1998 | . | | Bowie,Jim | Jul 6, 1998 | . | | Singer,Beth | Jun 29, 1998 | . | | Landgraf,Ralf | Jun 22, 1998 | . | | Kleiger,Gary | Jun 15, 1998 | . | | Balbirnie,Melinda | Jun 8, 1998 | . | | Pettit,Frank | May 25, 1998 | . | | Singer,Beth | May 18, 1998 | . | | Serag,Ahmed | May 11, 1998 | . | | Yeates,Todd | May 4, 1998 | . | | Weiss,Bob | Apr 27, 1998 | . | | Pellegrini,Matteo | Apr 20, 1998 | . | | Eisenberg,David | Apr 13, 1998 | . | | Mallick,Parag | Apr 6, 1998 | . | | Faham,Salem | Mar 23, 1998 | . | | Cascio,Duilio | Mar 9, 1998 | . | | Steere,Boyd | Mar 2, 1998 | . | | Grothe,Robert | Feb 23, 1998 | . | | Colovos,Chris | Feb 16, 1998 | . | | Pfluegl,Gaston | Jan 26, 1998 | . | | Toth,Eric | Jan 12, 1998 | . | | Padilla,Jennifer | Jan 5, 1998 | . | | Griffith,Scott | Dec 15, 1997 | . | | Marcotte,Edward | Dec 8, 1997 | . | | Fahrner,Rick | Dec 1, 1997 | . | | Dym,Orly | Nov 17, 1997 | . | | Dym,Orly | Nov 10, 1997 | . | | Kleiger,Gary | Nov 3, 1997 | . | | Landgraf,Ralf | Oct 20, 1997 | . | | Balbirnie,Melinda | Oct 13, 1997 | . | | Mura,Cameron | Oct 6, 1997 | . | | Bowie,Jim | Sep 22, 1997 | . | | Gill,Harry | Sep 15, 1997 | . | | Serag,Ahmed | Aug 25, 1997 | . | | Rice,Danny | Aug 11, 1997 | . | | Yeates,Todd | Aug 4, 1997 | . | | Weiss,Bob | Jul 28, 1997 | . | | Anderson,Daniel | Jul 14, 1997 | . | | Colovos,Chris | Jul 7, 1997 | . | | Singer,Beth | Jun 30, 1997 | . | | Fischer,Daniel | Jun 16, 1997 | . | | Pfluegl,Gaston | Jun 9, 1997 | . | | Toth,Eric | Jun 2, 1997 | . | | Eisenberg,David | May 12, 1997 | . | | Cascio,Duilio | May 5, 1997 | . | | Griffith,Scott | Apr 28, 1997 | . | | Marcotte,Edward | Apr 21, 1997 | . | | Fahrner,Rick | Apr 14, 1997 | . | | Pellegrini,Matteo | Mar 31, 1997 | . | | Dym,Orly | Mar 24, 1997 | . | | Steere,Boyd | Mar 10, 1997 | . | | Landgraf,Ralf | Feb 17, 1997 | . | | Balbirnie,Melinda | Feb 10, 1997 | . |
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