peter bowers
contact
welcome

205 MBI
Institute for Genomics and Proteomics
HHMI
University of California, Los Angeles
Los Angeles CA 90095
bowers@mbi.ucla.edu
310-825-1402
310-963-0284

Im interested in using computational biology to tackle interesting questions in biology, coupled with experimental validation and design. My long-term plans include interests in three general areas:

LOGIC ANALYSIS

A primary area of interest is the origins of complex traits, phenotypes, and disease states dictated by combinations of events. While individual mutations or proteins account for many of the phenotypes observed within or between populations, it is increasingly clear that combinations of loci act in concert to define diseases and complex traits. I am developing methods that can identify these events/loci from analysis of genomic data.

COMPARATIVE METHODS

Using comparative computational methods, including Rosetta Stone, Phylogenetic Profiles, Gene Neighbor and Gene Cluster, to discover novel cellular interactions and networks. We are using Escherichia coli as a model organism to validate our predictions.

BIOLOGICAL NETWORKS

Im interested in using genomic context (gene fusion, operon structure, ternary phylogenetic data) to elucidate the directional and conditional relationships of cellular networks.